The 77-year-old will give fans "a hilarious and insightful look" at his life both behind and in front of the cameras, producers said.
Audiences will also be able to ask King questions during the tour, which starts on 14 April in Connecticut.
Seven dates have been announced so far, the last being in Las Vegas on 11 June.
"Larry King's style and wit will give audiences an evening to remember," producers Base Entertainment and Karl Engemann said.
After King left his nightly talk show, former tabloid editor and talent show judge Piers Morgan stepped in to replace him.
The broadcaster will be interviewed by his successor in an edition of Piers Morgan Tonight to be aired later this week.
Morgan has said he expects there to be "a little tension in the air" when he sits down to quiz his predecessor.
In an interview with the BBC last week, King said he thought Morgan had been "oversold" to US TV audiences and that his show "might have been better off starting quietly".
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